Men of science from University of Cincinnati have discovered that applying a stem cell-infused bandage together with overexpression of a particular cell instruction particle promoted cell migration to damaged cardiac tissue coming after heart attack and ensued in ameliorated function in animal models.
The investigators also ascertained that function improved more systematic than when stem cells were directly put in heart tissue -- a therapy that's being analysed elsewhere.
"Following myocardial infarction, better known as heart attack, tissue becomes damaged and scarred, cardiomyocytes die and heart pump function is reduced," Wang says. "There are therapies being tested by other researchers where stem cells are injected directly into damaged heart muscle to see if contractile function can be restored."
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